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Target
D(2) dopamine receptor
Ligand
BDBM50003343
Substrate
n/a
Meas. Tech.
ChEBML_61768
IC50
12000±n/a nM
Citation
 Wikström, H; Andersson, B; Elebring, T; Lagerkvist, S; Hallnemo, G; Pettersson, I; Jovall, PA; Svensson, K; Ekman, A; Carlsson, A 6-Hydroxy-3-n-propyl-2,3,4,5-tetrahydro-1H-3-benzazepine and analogs: new centrally acting 5-HT1A receptor agonists. J Med Chem 35:3984-90 (1992) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50003343
Synonyms:
3-Butyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-6-ol | CHEMBL132112
Type:
Small organic molecule
Emp. Form.:
C14H21NO
Mol. Mass.:
219.3226
SMILES:
CCCCN1CCc2cccc(O)c2CC1
Structure:
Search PDB for entries with ligand similarity: