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TargetCatechol O-methyltransferase
LigandBDBM50004043
Substrate/Competitorn/a
Meas. Tech.ChEMBL_47058
IC50 2000±n/a nM
Citation Pérez, RAFernández-Alvarez, ENieto, OPiedrafita, FJ Dihydroxynitrobenzaldehydes and hydroxymethoxynitrobenzaldehydes: synthesis and biological activity as catechol-O-methyltransferase inhibitors. J Med Chem35:4584-8 (1993) [PubMed]  Article
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Catechol O-methyltransferase
Name:Catechol O-methyltransferase
Synonyms:COMT
Type:PROTEIN
Mol. Mass.:20586.58
Organism:Sus scrofa
Description:ChEMBL_105412
Residue:186
Sequence:
KERAMHVGRKKGQIVDTVVQEQRPSVLLELGAYCGYSAVRMARLLLPSARLLTIELNPDN
AAIAQQVVDFAGLQDRVTVVVGASQDIIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLE
ECGLLRKGTVLLADNVICPGAPDFLAHVRGCGRFECTHFSSYLEYSQMVDGLEKAVYKGP
GSPAQP
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BDBM50004043
NameBDBM50004043
Synonyms:3,4-Dihydroxy-5-Nitrobenzaldehyde (Rat) | 3,4-Dihydroxy-5-nitro-benzaldehyde | CHEMBL1244
TypeSmall organic molecule
Emp. Form.C7H5NO5
Mol. Mass.183.1183
SMILESOc1cc(C=O)cc(c1O)[N+]([O-])=O
Structure
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n/a