Target
Cholecystokinin receptor type A
Ligand
BDBM50005466
Substrate
n/a
Meas. Tech.
ChEMBL_47648 (CHEMBL657360)
Ki
340±n/a nM
Citation
 van der Bent, ABlommaert, AGMelman, CTIJzerman, APvan Wijngaarden, ISoudijn, W Hybrid cholecystokinin-A antagonists based on molecular modeling of lorglumide and L-364,718. J Med Chem 35:1042-9 (1992) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50005466
Synonyms:
1H-Indole-2-carboxylic acid (3,3-diphenyl-allyl)-amide | CHEMBL9500
Type:
Small organic molecule
Emp. Form.:
C24H20N2O
Mol. Mass.:
352.4284
SMILES:
O=C(NCC=C(c1ccccc1)c1ccccc1)c1cc2ccccc2[nH]1 |(6.59,-5.12,;7.37,-3.79,;6.61,-2.46,;5.07,-2.45,;4.25,-3.74,;2.71,-3.67,;1.99,-2.31,;.47,-2.24,;-.23,-.89,;.59,.41,;2.13,.34,;2.83,-1.01,;1.87,-4.97,;.33,-4.88,;-.51,-6.19,;.21,-7.57,;1.76,-7.64,;2.59,-6.33,;8.91,-3.8,;9.82,-2.55,;11.28,-3.04,;12.61,-2.29,;13.94,-3.06,;13.93,-4.6,;12.58,-5.35,;11.3,-4.7,;9.8,-5.05,)|
Structure:
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