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Target
Muscarinic acetylcholine receptor M2
Ligand
BDBM50006244
Substrate
n/a
Meas. Tech.
ChEMBL_140176 (CHEMBL745628)
Ki
5640±n/a nM
Citation
 De Amici, M; Dallanoce, C; De Micheli, C; Grana, E; Barbieri, A; Ladinsky, H; Schiavi, G; Zonta, F Synthesis and pharmacological investigation of the enantiomers of muscarone and allomuscarone. J Med Chem 35:1915-20 (1992) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M2
Synonyms:
ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51555.53
Organism:
RAT
Description:
P10980
Residue:
466
Sequence:
MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRIVKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
  
Inhibitor
Name:
BDBM50006244
Synonyms:
CHEMBL294470 | Trimethyl-(5-methyl-4-oxo-tetrahydro-furan-2-ylmethyl)-ammonium; iodide
Type:
Small organic molecule
Emp. Form.:
C9H18NO2
Mol. Mass.:
172.2442
SMILES:
C[C@H]1O[C@@H](C[N+](C)(C)C)CC1=O
Structure:
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