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Target
Cholesterol side-chain cleavage enzyme, mitochondrial
Ligand
BDBM9460
Substrate
n/a
Meas. Tech.
ChEBML_53758
IC50
29000±n/a nM
Citation
 Hartmann, RW; Batzl, C; Pongratz, TM; Mannschreck, A Synthesis and aromatase inhibition of 3-cycloalkyl-substituted 3-(4-aminophenyl)piperidine-2,6-diones. J Med Chem 35:2210-4 (1992) [PubMed]  Article 
Target
Name:
Cholesterol side-chain cleavage enzyme, mitochondrial
Synonyms:
CP11A_BOVIN | CYP11A1 | CYPXIA1 | Cholesterol desmolase | Cholesterol side-chain cleavage enzyme, mitochondrial | Cytochrome P450 11A1 | Cytochrome P450 11A1 (CYP11A1) | P450(scc)
Type:
Protein
Mol. Mass.:
60346.75
Organism:
Bos taurus (Bovine)
Description:
P00189
Residue:
520
Sequence:
MLARGLPLRSALVKACPPILSTVGEGWGHHRVGTGEGAGISTKTPRPYSEIPSPGDNGWLNLYHFWREKGSQRIHFRHIENFQKYGPIYREKLGNLESVYIIHPEDVAHLFKFEGSYPERYDIPPWLAYHRYYQKPIGVLFKKSGTWKKDRVVLNTEVMAPEAIKNFIPLLNPVSQDFVSLLHKRIKQQGSGKFVGDIKEDLFHFAFESITNVMFGERLGMLEETVNPEAQKFIDAVYKMFHTSVPLLNVPPELYRLFRTKTWRDHVAAWDTIFNKAEKYTEIFYQDLRRKTEFRNYPGILYCLLKSEKMLLEDVKANITEMLAGGVNTTSMTLQWHLYEMARSLNVQEMLREEVLNARRQAEGDISKMLQMVPLLKASIKETLRLHPISVTLQRYPESDLVLQDYLIPAKTLVQVAIYAMGRDPAFFSSPDKFDPTRWLSKDKDLIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHILENFKVEMQHIGDVDTIFNLILTPDKPIFLVFRPFNQDPPQA
  
Inhibitor
Name:
BDBM9460
Synonyms:
3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione | Aminoglutethimide AG, 4 | CHEMBL488 | Cytadren | EN300-53368 | Elipten | aminoglutethimide (AG)
Type:
Small organic molecule
Emp. Form.:
C13H16N2O2
Mol. Mass.:
232.2783
SMILES:
CCC1(CCC(=O)NC1=O)c1ccc(N)cc1
Structure:
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