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TargetMu-type opioid receptor
LigandBDBM50006999
Substrate/Competitorn/a
Meas. Tech.ChEMBL_146418
Ki>1000±n/a nM
Citation Freeman, JPMichalson, ETD'Andrea, SVBaczynskyj, LVon Voigtlander, PFLahti, RASmith, MWLawson, CFScahill, TAMizsak, SA Naphtho and benzo analogues of the kappa opioid agonist trans-(+/-)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl] benzeneacetamide. J Med Chem34:1891-6 (1991) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOR-1 | Mor | OPIATE Mu | Oprm | Oprm1
Type:Enzyme Catalytic Domain
Mol. Mass.:44431.62
Organism:MOUSE
Description:OPIATE Mu OPRM1 MOUSE::P42866
Residue:398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50006999
NameBDBM50006999
Synonyms:2-(3,4-Dichloro-phenyl)-N-(2-dimethylamino-1,2,3,4-tetrahydro-naphthalen-1-yl)-N-methyl-acetamide | CHEMBL293273
TypeSmall organic molecule
Emp. Form.C21H24Cl2N2O
Mol. Mass.391.334
SMILESCN(C)[C@@H]1CCc2ccccc2[C@H]1N(C)C(=O)Cc1ccc(Cl)c(Cl)c1
Structure
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n/a