Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50007157
Substrate
n/a
Meas. Tech.
ChEBML_146256
Ki
231±n/a nM
Citation
 Vecchietti, V; Clarke, GD; Colle, R; Giardina, G; Petrone, G; Sbacchi, M (1S)-1-(aminomethyl)-2-(arylacetyl)-1,2,3,4-tetrahydroisoquinoline and heterocycle-condensed tetrahydropyridine derivatives: members of a novel class of very potent kappa opioid analgesics. J Med Chem 34:2624-33 (1991) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50007157
Synonyms:
(-)-1-(1-Piperidin-1-ylmethyl-3,4-dihydro-1H-isoquinolin-2-yl)-2-(4-trifluoromethyl-phenyl)-ethanone;C4H6O6 | CHEMBL88393
Type:
Small organic molecule
Emp. Form.:
C24H27F3N2O
Mol. Mass.:
416.4792
SMILES:
FC(F)(F)c1ccc(CC(=O)N2CCc3ccccc3C2CN2CCCCC2)cc1
Structure:
Search PDB for entries with ligand similarity: