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Target
Delta-type opioid receptor
Ligand
BDBM50007325
Substrate
n/a
Meas. Tech.
ChEBML_146592
Ki
55±n/a nM
Citation
 Schiller, PW; Weltrowska, G; Nguyen, TM; Lemieux, C; Chung, NN; Marsden, BJ; Wilkes, BC Conformational restriction of the phenylalanine residue in a cyclic opioid peptide analogue: effects on receptor selectivity and stereospecificity. J Med Chem 34:3125-32 (1991) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40465.04
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor.
Residue:
372
Sequence:
MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50007325
Synonyms:
13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-2-benzyl-2-methyl-3,8,14-trioxo-1,4,9triaza-cyclotetradecane-5-carboxylic acid amide | CHEMBL325810
Type:
Small organic molecule
Emp. Form.:
C29H38N6O6
Mol. Mass.:
566.6486
SMILES:
C[C@]1(Cc2ccccc2)NC(=O)[C@@H](CCCNC(=O)CC[C@H](NC1=O)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1
Structure:
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