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Target
C5a anaphylatoxin chemotactic receptor 1
Ligand
BDBM50008381
Substrate
n/a
Meas. Tech.
ChEBML_41602
Ki
390±n/a nM
Citation
 Or, YS; Clark, RF; Lane, B; Mollison, KW; Carter, GW; Luly, JR Improvements in the minimum binding sequence of C5a: examination of His-67. J Med Chem 35:402-6 (1992) [PubMed]  Article 
Target
Name:
C5a anaphylatoxin chemotactic receptor 1
Synonyms:
C5AR | C5AR1 | C5AR1_HUMAN | C5R1 | C5a anaphylatoxin chemotactic receptor | C5a anaphylatoxin chemotactic receptor (C5aR) | C5a-R | CD_antigen=CD88
Type:
Enzyme
Mol. Mass.:
39347.68
Organism:
Homo sapiens (Human)
Description:
P21730
Residue:
350
Sequence:
MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
  
Inhibitor
Name:
BDBM50008381
Synonyms:
CHEMBL441393 | H-Ile-Ser-Phe-Lys-AspMet-GIn-Leu-Gly-Arg-OH | Ile-Ser-Phe-Lys-Asp-Met-Gln-Leu-Gly-Arg
Type:
Small organic molecule
Emp. Form.:
C52H87N15O15S
Mol. Mass.:
1194.404
SMILES:
CC[C@H](C)[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(O)=O
Structure:
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