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Target
D(3) dopamine receptor
Ligand
BDBM50259000
Substrate
n/a
Meas. Tech.
ChEBML_1691083
Ki
34±n/a nM
Citation
 Del Bello, F; Bonifazi, A; Giannella, M; Giorgioni, G; Piergentili, A; Petrelli, R; Cifani, C; Micioni Di Bonaventura, MV; Keck, TM; Mazzolari, A; Vistoli, G; Cilia, A; Poggesi, E; Matucci, R; Quaglia, W The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT Eur J Med Chem 125:233-244 (2017) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50259000
Synonyms:
CHEMBL4082195
Type:
Small organic molecule
Emp. Form.:
C25H27NO4
Mol. Mass.:
405.4862
SMILES:
Oc1ccccc1OCCNCC1COCC(O1)(c1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: