Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50009707
Substrate
n/a
Meas. Tech.
ChEBML_28553
IC50
9600±n/a nM
Citation
 Harden, FA; Quinn, RJ; Scammells, PJ Synthesis and adenosine receptor affinity of a series of pyrazolo[3,4-d]pyrimidine analogues of 1-methylisoguanosine. J Med Chem 34:2892-8 (1991) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50009707
Synonyms:
4-Amino-5-butyl-1-phenyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-6-one | CHEMBL95318
Type:
Small organic molecule
Emp. Form.:
C15H17N5O
Mol. Mass.:
283.3284
SMILES:
CCCCn1c(N)c2cnn(-c3ccccc3)c2nc1=O
Structure:
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