Reaction Details Report a problem with these data
Target
Estrogen-related receptor gamma
Ligand
BDBM29608
Substrate
n/a
Meas. Tech.
ChEBML_1696130
IC50
4.9±n/a nM
Citation
 Torikai, K; Koga, R; Liu, X; Umehara, K; Kitano, T; Watanabe, K; Oishi, T; Noguchi, H; Shimohigashi, Y Design and synthesis of benzoacridines as estrogenic and anti-estrogenic agents. Bioorg Med Chem 25:5216-5237 (2017) [PubMed]  Article 
Target
Name:
Estrogen-related receptor gamma
Synonyms:
ERR gamma-2 | ERR3 | ERR3_HUMAN | ERRG2 | ESRRG | Estrogen receptor-related protein 3 | Estrogen-Related Receptor, gamma | Estrogen-related receptor gamma | KIAA0832 | NR3B3 | Nuclear receptor subfamily 3 group B member 3
Type:
PROTEIN
Mol. Mass.:
51305.00
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1501351
Residue:
458
Sequence:
MDSVELCLPESFSLHYEEELLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV
  
Inhibitor
Name:
BDBM29608
Synonyms:
Bisphenol A (BPA) | Diphenylolpropane | US9688816, L
Type:
Small organic molecule
Emp. Form.:
C15H16O2
Mol. Mass.:
228.2863
SMILES:
CC(C)(c1ccc(O)cc1)c1ccc(O)cc1
Structure:
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