Reaction Details Report a problem with these data
Target
Histamine H3 receptor
Ligand
BDBM50406100
Substrate
n/a
Meas. Tech.
ChEBML_83827
Ki
200±n/a nM
Citation
 Timmerman, H Histamine H3 ligands: just pharmacological tools or potential therapeutic agents? J Med Chem 33:4-11 (1990) [PubMed]  Article 
Target
Name:
Histamine H3 receptor
Synonyms:
HH3R | HRH3_RAT | Hrh3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
48607.98
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
445
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK
  
Inhibitor
Name:
BDBM50406100
Synonyms:
CHEMBL12459
Type:
Small organic molecule
Emp. Form.:
C16H21N3O
Mol. Mass.:
271.3574
SMILES:
O=C(CCCCc1ccccc1)NCCc1cnc[nH]1
Structure:
Search PDB for entries with ligand similarity: