Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM50010697
Substrate
n/a
Meas. Tech.
ChEMBL_58644 (CHEMBL666358)
Ki
<10000±n/a nM
Citation
 Gao, YG; Baldessarini, RJ; Kula, NS; Neumeyer, JL Synthesis and dopamine receptor affinities of enantiomers of 2-substituted apomorphines and their N-n-propyl analogues. J Med Chem 33:1800-5 (1990) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50010697
Synonyms:
(R)-(-)-2-methoxyapomorphine | (R)-2-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | 2-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol | 2-methoxyapomorphine | CHEMBL53445
Type:
Small organic molecule
Emp. Form.:
C18H19NO3
Mol. Mass.:
297.3484
SMILES:
COc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 |r|
Structure:
Search PDB for entries with ligand similarity: