Reaction Details Report a problem with these data
Target
Platelet-activating factor receptor
Ligand
BDBM50011067
Substrate
n/a
Meas. Tech.
ChEBML_177423
IC50
2800±n/a nM
Citation
 Bartrolí, J; Carceller, E; Merlos, M; García-Rafanell, J; Forn, J Disubstituted tetrahydrofurans and dioxolanes and PAF antagonists. J Med Chem 34:373-86 (1991) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50011067
Synonyms:
1-Ethyl-2-[2-(4-hexadecyloxymethyl-tetrahydro-furan-2-ylmethoxycarbonylamino)-ethyl]-pyridinium; iodide | CHEMBL338260
Type:
Small organic molecule
Emp. Form.:
C32H57N2O4
Mol. Mass.:
533.8054
SMILES:
CCCCCCCCCCCCCCCCOCC1COC(COC(=O)NCCc2cccc[n+]2CC)C1
Structure:
Search PDB for entries with ligand similarity: