Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50007838
Substrate
n/a
Meas. Tech.
ChEBML_28998
Ki
0.300000±n/a nM
Citation
 Erickson, RH; Hiner, RN; Feeney, SW; Blake, PR; Rzeszotarski, WJ; Hicks, RP; Costello, DG; Abreu, ME 1,3,8-trisubstituted xanthines. Effects of substitution pattern upon adenosine receptor A1/A2 affinity. J Med Chem 34:1431-5 (1991) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50007838
Synonyms:
8-Cyclohexyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione | 8-Cyclohexyl-1,3-dipropyl-3,9-dihydro-purine-2,6-dione | CHEMBL160369
Type:
Small organic molecule
Emp. Form.:
C17H26N4O2
Mol. Mass.:
318.4139
SMILES:
CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCCC1
Structure:
Search PDB for entries with ligand similarity: