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Target
P2Y purinoceptor 2
Ligand
BDBM50271597
Substrate
n/a
Meas. Tech.
ChEMBL_1711179 (CHEMBL4121228)
Ki
1549±n/a nM
Citation
 Conroy, S; Kindon, ND; Glenn, J; Stoddart, LA; Lewis, RJ; Hill, SJ; Kellam, B; Stocks, MJ Synthesis and Evaluation of the First Fluorescent Antagonists of the Human P2Y J Med Chem 61:3089-3113 (2018) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 2
Synonyms:
ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2
Type:
PROTEIN
Mol. Mass.:
42299.21
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1455361
Residue:
377
Sequence:
MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL
  
Inhibitor
Name:
BDBM50271597
Synonyms:
CHEMBL4127983
Type:
Small organic molecule
Emp. Form.:
C18H14ClN3OS2
Mol. Mass.:
387.906
SMILES:
Cc1nc2C(c3ccc(Cl)cc3C=Cc2s1)c1cn(C)c(=O)[nH]c1=S |c:13|
Structure:
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