Reaction Details Report a problem with these data
Target
Ornithine decarboxylase
Ligand
BDBM50015683
Substrate
n/a
Meas. Tech.
ChEBML_147806
Ki
3000000±n/a nM
Citation
 Moyano, N; Frydman, J; Buldain, G; Ruiz, O; Frydman, RB Inhibition of ornithine decarboxylase by the isomers of 1,4-dimethylputrescine. J Med Chem 33:1969-74 (1990) [PubMed]  Article 
Target
Name:
Ornithine decarboxylase
Synonyms:
DCOR_RAT | Odc | Odc1
Type:
PROTEIN
Mol. Mass.:
51037.04
Organism:
Rattus norvegicus
Description:
ChEMBL_1344641
Residue:
461
Sequence:
MGSFTKEEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDVLKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPPERIIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMGTEVGFSMYLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQTGSDDEDESNEQTLMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCSLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRSMWQLMKQIQSHGFPPEVEEQDVGTLPMSCAQESGMDRHPAACASASINV
  
Inhibitor
Name:
BDBM50015683
Synonyms:
CHEMBL59625 | N*1*,N*1*-Dimethyl-butane-1,4-diamine
Type:
Small organic molecule
Emp. Form.:
C6H16N2
Mol. Mass.:
116.2046
SMILES:
CN(C)CCCCN
Structure:
Search PDB for entries with ligand similarity: