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Target
Vasopressin V2 receptor
Ligand
BDBM50016318
Substrate
n/a
Meas. Tech.
ChEMBL_214690 (CHEMBL817653)
Kd
46.0±n/a nM
Citation
 Grzonka, Z; Kasprzykowski, F; Kojro, E; Darlak, K; Melin, P; Fahrenholz, F; Crause, P; Boer, R Arginine-vasopressin analogues with high antidiuretic/vasopressor selectivity. Synthesis, biological activity, and receptor binding affinity of arginine-vasopressin analogues with substitutions in positions 1, 2, 4, 7, and 8. J Med Chem 29:96-9 (1986) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
AVPR2 | V2R_BOVIN | VASOPRESSIN V2 | Vasopressin V2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40248.83
Organism:
BOVINE
Description:
VASOPRESSIN V2 AVPR2 BOVINE::P48044
Residue:
370
Sequence:
MFMASTTSAVPWHLSQPTPAGNGSEGELLTARDPLLAQAELALLSTVFVAVALSNGLVLGALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAHRHGGGTHWNRPVLLAWAFSLLFSLPQLFIFAQRDVDGSGVLDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLGPGPVPRAGGPRRGCRPGSPAEGARVSAAVAKTVKMTLVIVIVYVLCWAPFFLVQLWAAWDPEAPREGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCTWRRAPPSPGPQEESCATASSFLAKDTPS
  
Inhibitor
Name:
BDBM50016318
Synonyms:
CHEMBL411357 | [Mpa1,MeAla7,D-Arg8]VP (Vasopressin )
Type:
Small organic molecule
Emp. Form.:
C45H64N14O12S2
Mol. Mass.:
1057.206
SMILES:
C[C@@H](N(C)C(=O)[C@@H]1CSSCCC(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N[C@H](CCCNC(N)=N)C(=O)NCC(N)=O
Structure:
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