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Target
Vasopressin V2 receptor
Ligand
BDBM50016310
Substrate
n/a
Meas. Tech.
ChEMBL_214691 (CHEMBL817654)
Kd
1.4±n/a nM
Citation
 Grzonka, Z; Kasprzykowski, F; Kojro, E; Darlak, K; Melin, P; Fahrenholz, F; Crause, P; Boer, R Arginine-vasopressin analogues with high antidiuretic/vasopressor selectivity. Synthesis, biological activity, and receptor binding affinity of arginine-vasopressin analogues with substitutions in positions 1, 2, 4, 7, and 8. J Med Chem 29:96-9 (1986) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
AVPR2 | V2R_BOVIN | VASOPRESSIN V2 | Vasopressin V2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40248.83
Organism:
BOVINE
Description:
VASOPRESSIN V2 AVPR2 BOVINE::P48044
Residue:
370
Sequence:
MFMASTTSAVPWHLSQPTPAGNGSEGELLTARDPLLAQAELALLSTVFVAVALSNGLVLGALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAHRHGGGTHWNRPVLLAWAFSLLFSLPQLFIFAQRDVDGSGVLDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLGPGPVPRAGGPRRGCRPGSPAEGARVSAAVAKTVKMTLVIVIVYVLCWAPFFLVQLWAAWDPEAPREGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCTWRRAPPSPGPQEESCATASSFLAKDTPS
  
Inhibitor
Name:
BDBM50016310
Synonyms:
CHEMBL406303 | [Mpa1Val4Sar7]AVP (Arginine-vasopressin )
Type:
Small organic molecule
Emp. Form.:
C44H63N13O11S2
Mol. Mass.:
1014.182
SMILES:
CC(C)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)CCSSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N(C)CC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O
Structure:
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