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Target
Beta-1 adrenergic receptor
Ligand
BDBM50017387
Substrate
n/a
Meas. Tech.
ChEBML_39187
IC50
2800±n/a nM
Citation
 Jamart-Gregoire, B; Caubere, P; Blanc, M; Gnassounou, JP; Advenier, C A new series of tricyclic (aryloximino)propanolamines displaying very high selective beta 2-blocking properties. J Med Chem 32:315-20 (1989) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | Adrenergic receptor | adrenergic Beta1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50540.48
Organism:
GUINEA PIG
Description:
adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73
Residue:
467
Sequence:
MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAGMGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVCTVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDEDEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
  
Inhibitor
Name:
BDBM50017387
Synonyms:
9a-Hydroxy-1,2,3,4,4a,9a-hexahydro-fluoren-9-one O-(3-tert-butylamino-2-hydroxy-propyl)-oxime | CHEMBL320704
Type:
Small organic molecule
Emp. Form.:
C20H30N2O3
Mol. Mass.:
346.4638
SMILES:
CC(C)(C)NCC(O)CO\N=C1\c2ccccc2C2CCCCC12O
Structure:
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