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Target
Beta-1 adrenergic receptor
Ligand
BDBM50017389
Substrate
n/a
Meas. Tech.
ChEBML_39187
IC50
>10000±n/a nM
Citation
 Jamart-Gregoire, B; Caubere, P; Blanc, M; Gnassounou, JP; Advenier, C A new series of tricyclic (aryloximino)propanolamines displaying very high selective beta 2-blocking properties. J Med Chem 32:315-20 (1989) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | Adrenergic receptor | adrenergic Beta1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50540.48
Organism:
GUINEA PIG
Description:
adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73
Residue:
467
Sequence:
MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAGMGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVCTVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDEDEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
  
Inhibitor
Name:
BDBM50017389
Synonyms:
13a-Methoxy-5,6,7,8,9,10,11,12,13,13a-decahydro-4bH-cycloundeca[a]inden-14-one O-{3-[2-(3,5-dimethoxy-phenyl)-ethylamino]-2-hydroxy-propyl}-oxime | CHEMBL111415
Type:
Small organic molecule
Emp. Form.:
C32H46N2O5
Mol. Mass.:
538.718
SMILES:
COc1cc(CCNCC(O)CO\N=C2\c3ccccc3C3CCCCCCCCCC23OC)cc(OC)c1
Structure:
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