Reaction Details Report a problem with these data
Target
Papain
Ligand
BDBM50018173
Substrate
n/a
Meas. Tech.
ChEMBL_152652 (CHEMBL763841)
pH
7±n/a
Ki
30000±n/a nM
Comments
extracted
Citation
 Silver, MS; Haskell, JH Acid-sensitive latent inhibitors for proteolytic enzymes: synthesis and characterization. J Med Chem 32:1253-9 (1989) [PubMed]  Article 
Target
Name:
Papain
Synonyms:
Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I
Type:
Enzyme
Mol. Mass.:
38923.01
Organism:
Carica papaya
Description:
Papain was purchased from Sigma, Germany.
Residue:
345
Sequence:
MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYGPNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
  
Inhibitor
Name:
BDBM50018173
Synonyms:
CHEMBL22745 | N-{2-[(2-Acetylamino-propionyl)-hydrazono]-ethyl}-benzamide
Type:
Small organic molecule
Emp. Form.:
C14H18N4O3
Mol. Mass.:
290.3177
SMILES:
C[C@H](NC(C)=O)C(=O)NN=CCNC(=O)c1ccccc1 |w:10.10|
Structure:
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