Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50455533
Substrate
n/a
Meas. Tech.
ChEMBL_1754701 (CHEMBL4189461)
Ki
0.180000±n/a nM
Citation
 Köse, M; Gollos, S; Karcz, T; Fiene, A; Heisig, F; Behrenswerth, A; Kie?-Kononowicz, K; Namasivayam, V; Müller, CE Fluorescent-Labeled Selective Adenosine A J Med Chem 61:4301-4316 (2018) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_RAT | Adenosine receptor | Adora2b
Type:
PROTEIN
Mol. Mass.:
36378.84
Organism:
Rattus norvegicus
Description:
ChEMBL_32934
Residue:
332
Sequence:
MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL
  
Inhibitor
Name:
BDBM50455533
Synonyms:
CHEMBL4205635
Type:
Small organic molecule
Emp. Form.:
C31H34BF2N7O4
Mol. Mass.:
617.454
SMILES:
CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1ccc(OCC(=O)NCCC2=C3C(C)=CC(C)=[N+]3[B-](F)(F)n3c(C)cc(C)c23)cc1 |c:27,30,33|
Structure:
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