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Targetadrenergic Alpha2
LigandBDBM31005
Substrate/Competitorn/a
Meas. Tech.ChEMBL_33031
Ki 17±n/a nM
Citation Saari, WSHalczenko, WKing, SWHuff, JRGuare, JPHunt, CARandall, WCAnderson, PSLotti, VJTaylor, DA Pyridinylpiperazines, a new class of selective alpha 2-adrenoceptor antagonists. J Med Chem26:1696-701 (1984) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
adrenergic Alpha2
Name:adrenergic Alpha2
Synonyms:Alpha-2A adrenergic receptor | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | Alpha-2D adrenergic receptor | Alpha-2Da adrenergic receptor | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha2A | adrenergic Alpha2D
Type:Enzyme Catalytic Domain
Mol. Mass.:49275.13
Organism:BOVINE
Description:adrenergic Alpha2 0 BOVINE::Q28838
Residue:452
Sequence:
MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISFEKKRGRSG
QPSAEPRCEINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDATA
AELPGSAERRPNGLGPERGGVGPVGAEVESLQVQLNGAPGEPAPAGAGADALDLEESSSS
EHAERPPGSRRSERGPRAKGKARASQVKPGDSLPRRGPGATGLGAPTAGPAEERSGGGAK
ASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAIGCPVPPTLFKFFFWFGYCN
SSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
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  Blast E-value cutoff:
BDBM31005
n/a
NameBDBM31005
Synonyms:2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine | MIANSERIN HYDROCHLORIDE | MLS000069681 | SMR000058472 | cid_68551
TypeSmall organic molecule
Emp. Form.C18H21ClN2
Mol. Mass.300.826
SMILESCl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21
Structure
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