Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetSerine protease 1
LigandBDBM50472494
Substrate/Competitorn/a
Meas. Tech.ChEMBL_213236
Ki 99999999999999±n/a nM
Citation Böhm, MSt rzebecher, JKlebe, G Three-dimensional quantitative structure-activity relationship analyses using comparative molecular field analysis and comparative molecular similarity indices analysis to elucidate selectivity differences of inhibitors binding to trypsin, thrombin, and factor Xa. J Med Chem42:458-77 (1999) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Serine protease 1
Name:Serine protease 1
Synonyms:Beta-Trypsin | Cationic trypsin | Trypsin | Trypsin I
Type:Enzyme
Mol. Mass.:25790.52
Organism:Bos taurus (bovine)
Description:P00760
Residue:246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50472494
NameBDBM50472494
Synonyms:CHEMBL1161253
TypeSmall organic molecule
Emp. Form.C26H28N4O5S
Mol. Mass.508.589
SMILESNC(=N)c1cccc(C[C@H](NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCC[C@@H]2C(O)=O)c1 |r|
Structure
n/a