Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50032589
Substrate
n/a
Meas. Tech.
ChEMBL_46818 (CHEMBL857785)
Ki
125892541±n/a nM
Citation
 Tetko, IV; Kovalishyn, VV; Livingstone, DJ Volume learning algorithm artificial neural networks for 3D QSAR studies. J Med Chem 44:2411-20 (2001) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50032589
Synonyms:
CHEMBL78415 | [7-Methoxy-2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-naphthalen-1-yl-methanone
Type:
Small organic molecule
Emp. Form.:
C27H28N2O3
Mol. Mass.:
428.5228
SMILES:
COc1cccc2c(C(=O)c3cccc4ccccc34)c(C)n(CCN3CCOCC3)c12
Structure:
Search PDB for entries with ligand similarity: