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Target
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Ligand
BDBM50473784
Substrate
n/a
Meas. Tech.
ChEMBL_162010 (CHEMBL764181)
Kd
1413±n/a nM
Citation
 Ishchenko, AV; Shakhnovich, EI SMall Molecule Growth 2001 (SMoG2001): an improved knowledge-based scoring function for protein-ligand interactions. J Med Chem 45:2770-80 (2002) [PubMed]  Article 
Target
Name:
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Synonyms:
2A5A_HUMAN | PPP2R5A | Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Type:
PROTEIN
Mol. Mass.:
56194.06
Organism:
Homo sapiens (Human)
Description:
ChEMBL_161424
Residue:
486
Sequence:
MSSSSPPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLKDATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNSAYNMHSILSNTSAE
  
Inhibitor
Name:
BDBM50473784
Synonyms:
CHEMBL95058
Type:
Small organic molecule
Emp. Form.:
C10H16N4O16P4
Mol. Mass.:
572.1463
SMILES:
O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cnc2cncnc12
Structure:
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