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Target
Ornithine decarboxylase
Ligand
BDBM50028200
Substrate
n/a
Meas. Tech.
ChEBML_148131
Ki
2700±n/a nM
Citation
 Bey, P; Gerhart, F; Van Dorsselaer, V; Danzin, C alpha-(Fluoromethyl)dehydroornithine and alpha-(fluoromethyl)dehydroputrescine analogues as irreversible inhibitors of ornithine decarboxylase. J Med Chem 26:1551-6 (1983) [PubMed]  Article 
Target
Name:
Ornithine decarboxylase
Synonyms:
DCOR_RAT | Odc | Odc1
Type:
PROTEIN
Mol. Mass.:
51037.04
Organism:
Rattus norvegicus
Description:
ChEMBL_1344641
Residue:
461
Sequence:
MGSFTKEEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDVLKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPPERIIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMGTEVGFSMYLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQTGSDDEDESNEQTLMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCSLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRSMWQLMKQIQSHGFPPEVEEQDVGTLPMSCAQESGMDRHPAACASASINV
  
Inhibitor
Name:
BDBM50028200
Synonyms:
2,5-Diamino-2-methyl-pent-3-enoic acid | CHEMBL40051
Type:
Small organic molecule
Emp. Form.:
C6H12N2O2
Mol. Mass.:
144.1717
SMILES:
CC(N)(\C=C\CN)C(O)=O
Structure:
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