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TargetHIV-1 protease
LigandBDBM81673
Substrate/Competitorn/a
Meas. Tech.ChEMBL_517306
Ki 58±n/a nM
Citation Jorissen, RNReddy, GSAli, AAltman, MDChellappan, SAnjum, SGTidor, BSchiffer, CARana, TMGilson, MK Additivity in the analysis and design of HIV protease inhibitors. J Med Chem52:737-54 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
HIV-1 protease
Name:HIV-1 protease
Synonyms:HIV-1 | HIV-1 protease | protease
Type:PROTEIN
Mol. Mass.:10795.19
Organism:Human immunodeficiency virus
Description:ChEMBL_118439
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM81673
NameBDBM81673
Synonyms:CARB-KB45
TypeSmall organic molecule
Emp. Form.C23H31N3O6S
Mol. Mass.477.574
SMILESCNC(=O)CCC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC1CC1)S(=O)(=O)c1ccco1 |r|
Structure
n/a