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TargetProtease
LigandBDBM50483074
Substrate/Competitorn/a
Meas. Tech.ChEMBL_685646
Ki 0.097000±n/a nM
Citation Ali, AReddy, GSNalam, MNAnjum, SGCao, HSchiffer, CARana, TM Structure-based design, synthesis, and structure-activity relationship studies of HIV-1 protease inhibitors incorporating phenyloxazolidinones. J Med Chem53:7699-708 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Protease
Name:Protease
Synonyms:n/a
Type:Enzyme
Mol. Mass.:10904.79
Organism:Human immunodeficiency virus 1 (HIV-1)
Description:Q9YQ12
Residue:99
Sequence:
PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50483074
NameBDBM50483074
Synonyms:CHEMBL1233804
TypeSmall organic molecule
Emp. Form.C32H33F3N4O6S2
Mol. Mass.690.753
SMILESCC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CN(C(=O)O1)c1ccccc1C(F)(F)F)S(=O)(=O)c1ccc2ncsc2c1 |r|
Structure
n/a