Reaction Details Report a problem with these data
Target
Solute carrier family 15 member 2
Ligand
BDBM50188516
Substrate
n/a
Meas. Tech.
ChEMBL_836690 (CHEMBL2077645)
Ki
64000±n/a nM
Citation
 Ganapathy, ME; Brandsch, M; Prasad, PD; Ganapathy, V; Leibach, FH Differential recognition of beta -lactam antibiotics by intestinal and renal peptide transporters, PEPT 1 and PEPT 2. J Biol Chem 270:25672-7 (1995) [PubMed]  Article 
Target
Name:
Solute carrier family 15 member 2
Synonyms:
Kidney H(+)/peptide cotransporter | Oligopeptide transporter, kidney isoform | PEPT2 | Peptide transporter 2 | S15A2_HUMAN | SLC15A2
Type:
PROTEIN
Mol. Mass.:
81795.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_762551
Residue:
729
Sequence:
MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIVVNEFCERFSYYGMKAVLILYFLYFLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVIKSLGALPILGGQVVHTVLSLIGLSLIALGTGGIKPCVAAFGGDQFEEKHAEERTRYFSVFYLSINAGSLISTFITPMLRGDVQCFGEDCYALAFGVPGLLMVIALVVFAMGSKIYNKPPPEGNIVAQVFKCIWFAISNRFKNRSGDIPKRQHWLDWAAEKYPKQLIMDVKALTRVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLGFFVLQPDQMQVLNPLLVLIFIPLFDFVIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINEMAPAQPGPQEVFLQVLNLADDEVKVTVVGNENNSLLIESIKSFQKTPHYSKLHLKTKSQDFHFHLKYHNLSLYTEHSVQEKNWYSLVIREDGNSISSMMVKDTESRTTNGMTTVRFVNTLHKDVNISLSTDTSLNVGEDYGVSAYRTVQRGEYPAVHCRTEDKNFSLNLGLLDFGAAYLFVITNNTNQGLQAWKIEDIPANKMSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVGNIIVLVVAQFSGLVQWAEFILFSCLLLVICLIFSIMGYYYVPVKTEDMRGPADKHIPHIQGNMIKLETKKTKL
  
Inhibitor
Name:
BDBM50188516
Synonyms:
2-(2-amino-N-methylacetamido)acetic acid | CHEMBL175737 | Gly-Sar | Gly-sarcosin | [(2-Amino-acetyl)-methyl-amino]-acetic acid | [(ammonioacetyl)(methyl)amino]acetate
Type:
Small organic molecule
Emp. Form.:
C5H10N2O3
Mol. Mass.:
146.1445
SMILES:
CN(CC(O)=O)C(=O)CN
Structure:
Search PDB for entries with ligand similarity: