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Target
Integrase
Ligand
BDBM50029212
Substrate
n/a
Meas. Tech.
ChEMBL_88620 (CHEMBL701724)
IC50
55000±n/a nM
Citation
 Burke, TR; Fesen, MR; Mazumder, A; Wang, J; Carothers, AM; Grunberger, D; Driscoll, J; Kohn, K; Pommier, Y Hydroxylated aromatic inhibitors of HIV-1 integrase. J Med Chem 38:4171-8 (1995) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
Human immunodeficiency virus type 1 integrase
Type:
PROTEIN
Mol. Mass.:
32231.48
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_90865
Residue:
288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50029212
Synonyms:
(E)-3-(2,4,5-Trihydroxy-phenyl)-acrylic acid phenethyl ester | 3-(2,4,5-Trihydroxy-phenyl)-acrylic acid phenethyl ester | CHEMBL131749
Type:
Small organic molecule
Emp. Form.:
C17H16O5
Mol. Mass.:
300.3059
SMILES:
Oc1cc(O)c(\C=C\C(=O)OCCc2ccccc2)cc1O
Structure:
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