Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50069907
Substrate
n/a
Meas. Tech.
ChEMBL_932180 (CHEMBL3073098)
Ki
5.5±n/a nM
Citation
  TBA Med Chem Res 22:520-530 (2013)    Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50069907
Synonyms:
1-benzyl-4-(3-hydroxyphenyl)piperazine | 3-(4-Benzyl-piperazin-1-yl)-phenol | CHEMBL88365
Type:
Small organic molecule
Emp. Form.:
C17H20N2O
Mol. Mass.:
268.3535
SMILES:
Oc1cccc(c1)N1CCN(Cc2ccccc2)CC1
Structure:
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