Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM50036842
Substrate
n/a
Meas. Tech.
ChEMBL_37846 (CHEMBL656008)
IC50
269.15±n/a nM
Citation
 Macchia, B; Balsamo, A; Breschi, MC; Chiellini, G; Macchia, M; Martinelli, A; Martini, C; Nardini, C; Nencetti, S; Rossello, A The [(methyloxy)imino]methyl moiety as a bioisoster of aryl. A novel class of completely aliphatic beta-adrenergic receptor antagonists. J Med Chem 37:1518-25 (1994) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2_CAVPO | Adrb2 | adrenergic Beta2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46993.24
Organism:
GUINEA PIG
Description:
adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4
Residue:
418
Sequence:
MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
  
Inhibitor
Name:
BDBM50036842
Synonyms:
3-tert-Butylamino-2-hydroxy-propionaldehyde O-propyl-oxime; compound with (E)-but-2-enedioic acid | CHEMBL39706
Type:
Small organic molecule
Emp. Form.:
C10H22N2O2
Mol. Mass.:
202.2939
SMILES:
CCCO\N=C\C(O)CNC(C)(C)C
Structure:
Search PDB for entries with ligand similarity: