Target
Beta-2 adrenergic receptor
Ligand
BDBM50036843
Substrate
n/a
Meas. Tech.
ChEMBL_37846 (CHEMBL656008)
IC50
12882.5±n/a nM
Citation
 Macchia, BBalsamo, ABreschi, MCChiellini, GMacchia, MMartinelli, AMartini, CNardini, CNencetti, SRossello, A The [(methyloxy)imino]methyl moiety as a bioisoster of aryl. A novel class of completely aliphatic beta-adrenergic receptor antagonists. J Med Chem 37:1518-25 (1994) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2_CAVPO | Adrb2 | adrenergic Beta2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46993.24
Organism:
GUINEA PIG
Description:
adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4
Residue:
418
Sequence:
MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
  
Inhibitor
Name:
BDBM50036843
Synonyms:
Acetaldehyde O-(2-hydroxy-3-isopropylamino-propyl)-oxime; compound with (E)-but-2-enedioic acid | CHEMBL290153
Type:
Small organic molecule
Emp. Form.:
C8H18N2O2
Mol. Mass.:
174.2407
SMILES:
C\C=N\OCC(O)CNC(C)C
Structure:
Search PDB for entries with ligand similarity: