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Target
Beta-1 adrenergic receptor
Ligand
BDBM50036842
Substrate
n/a
Meas. Tech.
ChEMBL_39169 (CHEMBL654466)
IC50
8318±n/a nM
Citation
 Macchia, B; Balsamo, A; Breschi, MC; Chiellini, G; Macchia, M; Martinelli, A; Martini, C; Nardini, C; Nencetti, S; Rossello, A The [(methyloxy)imino]methyl moiety as a bioisoster of aryl. A novel class of completely aliphatic beta-adrenergic receptor antagonists. J Med Chem 37:1518-25 (1994) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | Adrenergic receptor | adrenergic Beta1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50540.48
Organism:
GUINEA PIG
Description:
adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73
Residue:
467
Sequence:
MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAGMGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVCTVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDEDEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
  
Inhibitor
Name:
BDBM50036842
Synonyms:
3-tert-Butylamino-2-hydroxy-propionaldehyde O-propyl-oxime; compound with (E)-but-2-enedioic acid | CHEMBL39706
Type:
Small organic molecule
Emp. Form.:
C10H22N2O2
Mol. Mass.:
202.2939
SMILES:
CCCO\N=C\C(O)CNC(C)(C)C
Structure:
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