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Target
Adenosine deaminase
Ligand
BDBM50037902
Substrate
n/a
Meas. Tech.
ChEMBL_30936 (CHEMBL646740)
Ki
6.4±n/a nM
Citation
 Vargeese, C; Sarma, MS; Pragnacharyulu, PV; Abushanab, E; Li, SY; Stoeckler, JD Adenosine deaminase inhibitors. Synthesis and biological evaluation of putative metabolites of (+)-erythro-9-(2S-hydroxy-3R-nonyl)adenine. J Med Chem 37:3844-9 (1994) [PubMed]  Article 
Target
Name:
Adenosine deaminase
Synonyms:
ADA | ADA_BOVIN | Adenosine aminohydrolase
Type:
Enzyme
Mol. Mass.:
40910.44
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
363
Sequence:
MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPEFLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAIDLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGYHTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIFKSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAEQCL
  
Inhibitor
Name:
BDBM50037902
Synonyms:
6-Amino-9-[(R)-1-((S)-1-hydroxy-ethyl)-heptyl]-9H-purin-8-ol | CHEMBL123910
Type:
Small organic molecule
Emp. Form.:
C14H23N5O2
Mol. Mass.:
293.3647
SMILES:
CCCCCC[C@H]([C@H](C)O)n1c2ncnc(N)c2[nH]c1=O
Structure:
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