Reaction Details Report a problem with these data
Target
Muscarinic acetylcholine receptor
Ligand
BDBM50038213
Substrate
n/a
Meas. Tech.
ChEMBL_138227 (CHEMBL744918)
EC50
4400±n/a nM
Citation
 Moltzen, EK; Pedersen, H; Bøgesø, KP; Meier, E; Frederiksen, K; Sánchez, C; Løve Lembøl, H Bioisosteres of arecoline: 1,2,3,6-tetrahydro-5-pyridyl-substituted and 3-piperidyl-substituted derivatives of tetrazoles and 1,2,3-triazoles. Synthesis and muscarinic activity. J Med Chem 37:4085-99 (1995) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor
Synonyms:
GPM3 | Muscarinic acetylcholine receptor M3
Type:
n/a
Mol. Mass.:
66272.13
Organism:
Cavia porcellus
Description:
n/a
Residue:
587
Sequence:
MTLHSNSTTLPLFPNISTSWIHSPSEAGLPPGTVTHFGSYNISQAAGNFSSLNGTTSDPLGGHTIWQVVFIAFLTGFLALVTIIGNILVIVSFKVNKQLKHVNNYFLLSLADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSLKHSSRRKYSRCHFWFATKSWKPNAGQMDQDHSSSDSWNNYDAAASLENSASDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEDLEPMDMERNASKPQTQKSMDDGGSFQKSFSNLPIQLESTMDTAKTSDANSSVSKTMATLPLSFKEATLAKRFALRTRSQITKRKRMSLIKEKRAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNPVCYALCNKTFRNTFKMLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL
  
Inhibitor
Name:
BDBM50038213
Synonyms:
3-(2-Allyl-2H-[1,2,3]triazol-4-yl)-piperidine | CHEMBL131777
Type:
Small organic molecule
Emp. Form.:
C10H16N4
Mol. Mass.:
192.2608
SMILES:
C=CCn1ncc(n1)C1CCCNC1
Structure:
Search PDB for entries with ligand similarity: