Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50020222
Substrate
n/a
Meas. Tech.
ChEMBL_61343 (CHEMBL675959)
Ki
142±n/a nM
Citation
 Chumpradit, S; Kung, MP; Vessotskie, J; Foulon, C; Mu, M; Kung, HF Iodinated 2-aminotetralins and 3-amino-1-benzopyrans: ligands for dopamine D2 and D3 receptors. J Med Chem 37:4245-50 (1995) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50020222
Synonyms:
(+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol | (+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin | (R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol | 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol | 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol | 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN) | 7-OH-DPAT | 7-OH-DPAT,(+) | 7-OH-DPAT,(-) | 7-hydroxy-2-(dipropylamino)tetralin | CHEMBL1255966 | CHEMBL285755
Type:
Small organic molecule
Emp. Form.:
C16H25NO
Mol. Mass.:
247.3758
SMILES:
CCCN(CCC)C1CCc2ccc(O)cc2C1
Structure:
Search PDB for entries with ligand similarity: