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TargetProtease
LigandBDBM50489369
Substrate/Competitorn/a
Meas. Tech.ChEMBL_981453
Ki 5.9±n/a nM
Citation Ghosh, AKParham, GLMartyr, CDNyalapatla, PROsswald, HLAgniswamy, JWang, YFAmano, MWeber, ITMitsuya, H Highly potent HIV-1 protease inhibitors with novel tricyclic P2 ligands: design, synthesis, and protein-ligand X-ray studies. J Med Chem56:6792-802 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Protease
Name:Protease
Synonyms:n/a
Type:Enzyme
Mol. Mass.:10904.79
Organism:Human immunodeficiency virus 1 (HIV-1)
Description:Q9YQ12
Residue:99
Sequence:
PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50489369
NameBDBM50489369
Synonyms:CHEMBL1232930 | GRL-0519
TypeSmall organic molecule
Emp. Form.C30H40N2O9S
Mol. Mass.604.712
SMILES[H][C@@]12OCC[C@]1([H])[C@@]1([H])[C@H](CO[C@@]1([H])O2)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc(OC)cc1 |r|
Structure
n/a