Reaction Details Report a problem with these data
Target
Protease
Ligand
BDBM50489369
Substrate
n/a
Meas. Tech.
ChEMBL_981453 (CHEMBL2428516)
Ki
0.006±n/a nM
Citation
Ghosh, AK; Parham, GL; Martyr, CD; Nyalapatla, PR; Osswald, HL; Agniswamy, J; Wang, YF; Amano, M; Weber, IT; Mitsuya, H Highly potent HIV-1 protease inhibitors with novel tricyclic P2 ligands: design, synthesis, and protein-ligand X-ray studies. J Med Chem 56:6792-802 (2013) [PubMed] Article
More Info.:
Target
Name:
Protease
Synonyms:
n/a
Type:
Enzyme
Mol. Mass.:
10904.79
Organism:
Human immunodeficiency virus 1 (HIV-1)
Description:
Q9YQ12
Residue:
99
Sequence:
PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF