Reaction Details Report a problem with these data
Target
Somatostatin receptor type 1
Ligand
BDBM50192018
Substrate
n/a
Meas. Tech.
ChEMBL_1282233 (CHEMBL3102458)
Ki
300±n/a nM
Citation
 Martín-Gago, P; Ramón, R; Aragón, E; Fernández-Carneado, J; Martin-Malpartida, P; Verdaguer, X; López-Ruiz, P; Colás, B; Cortes, MA; Ponsati, B; Macias, MJ; Riera, A A tetradecapeptide somatostatin dicarba-analog: Synthesis, structural impact and biological activity. Bioorg Med Chem Lett 24:103-7 (2014) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 1
Synonyms:
SOMATOSTATIN SST1 | SRIF-2 | SS-1-R | SS1-R | SS1R | SSR1_HUMAN | SSTR1 | Somatostatin receptor type 1 (SSTR1)
Type:
Enzyme
Mol. Mass.:
42692.81
Organism:
Homo sapiens (Human)
Description:
P30872
Residue:
391
Sequence:
MFPNGTASSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCTSRITTL
  
Inhibitor
Name:
BDBM50192018
Synonyms:
CHEMBL3350037
Type:
Small organic molecule
Emp. Form.:
C49H66N10O10S2
Mol. Mass.:
1019.239
SMILES:
[H][C@]1(NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](CO)[C@@H](C)O)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)O |r|
Structure:
Search PDB for entries with ligand similarity: