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Target
Adenosine receptor A1
Ligand
BDBM50011216
Substrate
n/a
Meas. Tech.
ChEMBL_29299 (CHEMBL640360)
Ki
32.6±n/a nM
Citation
 Peet, NP; Lentz, NL; Dudley, MW; Ogden, AM; McCarty, DR; Racke, MM Xanthines with C8 chiral substituents as potent and selective adenosine A1 antagonists. J Med Chem 36:4015-20 (1994) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50011216
Synonyms:
1-Methyl-8-(1-methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine-2,6-dione | 8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione | 8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine-2,6-dione | CHEMBL337073
Type:
Small organic molecule
Emp. Form.:
C20H26N4O2
Mol. Mass.:
354.446
SMILES:
CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C(C)Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: