Reaction Details Report a problem with these data
Target
Somatostatin receptor type 4
Ligand
BDBM50068039
Substrate
n/a
Meas. Tech.
ChEMBL_1330642 (CHEMBL3222547)
Ki
17±n/a nM
Citation
 Marugan, JJ; Huang, W; Motabar, O; Zheng, W; Xiao, J; Patnaik, S; Southall, N; Westbroek, W; Lea, WA; Simeonov, A; Goldin, E; Debernardi, MA; Sidransky, E Non-iminosugar glucocerebrosidase small molecule chaperones. Medchemcomm 3:56-60 (2012) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM50068039
Synonyms:
1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)-amino]-propyl}-3-[3-(1H-imidazol-4-yl)-propyl]-thiourea | CHEMBL103769
Type:
Small organic molecule
Emp. Form.:
C22H25BrCl2N6S
Mol. Mass.:
556.349
SMILES:
Clc1ccc(CN(CCCNC(=S)NCCCc2cnc[nH]2)c2ccc(Br)cn2)cc1Cl
Structure:
Search PDB for entries with ligand similarity: