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Reaction Details
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TargetPlatelet activating factor receptor
LigandBDBM50045959
Substrate/Competitorn/a
Meas. Tech.ChEMBL_151692
IC50 13±n/a nM
Citation Carceller, EMerlos, MGiral, MAlmansa, CBartrolí, JGarcía-Rafanell, JForn, J Synthesis and structure-activity relationships of 1-acyl-4-((2-methyl-3-pyridyl)cyanomethyl)piperazines as PAF antagonists. J Med Chem36:2984-97 (1993) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Platelet activating factor receptor
Name:Platelet activating factor receptor
Synonyms:PAF-R | Platelet-activating factor receptor
Type:Protein
Mol. Mass.:39005.63
Organism:Cavia porcellus
Description:n/a
Residue:342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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  Blast E-value cutoff:
BDBM50045959
NameBDBM50045959
Synonyms:CHEMBL103476 | {4-[2-(Benzhydryl-amino)-propionyl]-piperazin-1-yl}-(2-methyl-pyridin-3-yl)-acetonitrile
TypeSmall organic molecule
Emp. Form.C28H31N5O
Mol. Mass.453.5786
SMILESC[C@H](NC(c1ccccc1)c1ccccc1)C(=O)N1CCN(CC1)C(C#N)c1cccnc1C
Structure
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n/a