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Target
D(2) dopamine receptor
Ligand
BDBM50047436
Substrate
n/a
Meas. Tech.
ChEBML_62225
Ki
1.3±n/a nM
Citation
 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Bridged gamma-carbolines and derivatives possessing selective and combined affinity for 5-HT2 and D2 receptors. J Med Chem 36:1488-95 (1993) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50047436
Synonyms:
8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-8-aza-bicyclo[3.2.1]octan-3-one | CHEMBL35536
Type:
Small organic molecule
Emp. Form.:
C17H20FNO2
Mol. Mass.:
289.3446
SMILES:
Fc1ccc(cc1)C(=O)CCCN1C2CCC1CC(=O)C2 |THB:19:18:12:14.15|
Structure:
Search PDB for entries with ligand similarity: