Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50051338
Substrate
n/a
Meas. Tech.
ChEMBL_30474 (CHEMBL640329)
Ki
12300±n/a nM
Citation
 Karton, Y; Jiang, JL; Ji, XD; Melman, N; Olah, ME; Stiles, GL; Jacobson, KA Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists. J Med Chem 39:2293-301 (1996) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3
Type:
PROTEIN
Mol. Mass.:
36643.73
Organism:
Rattus norvegicus
Description:
ChEMBL_479910
Residue:
320
Sequence:
MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE
  
Inhibitor
Name:
BDBM50051338
Synonyms:
4-Ethoxy-7-((E)-styryl)-furo[3,2-g]chromen-5-one | CHEMBL76874
Type:
Small organic molecule
Emp. Form.:
C21H16O4
Mol. Mass.:
332.3493
SMILES:
CCOc1c2ccoc2cc2oc(\C=C\c3ccccc3)cc(=O)c12
Structure:
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