Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50051672
Substrate
n/a
Meas. Tech.
ChEMBL_29636 (CHEMBL639743)
Ki
2.6±n/a nM
Citation
 Müller, CE; Geis, U; Grahner, B; Lanzner, W; Eger, K Chiral pyrrolo[2,3-d]pyrimidine and pyrimido[4,5-b]indole derivatives: structure-activity relationships of potent, highly stereoselective A1-adenosine receptor antagonists. J Med Chem 39:2482-91 (1996) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50051672
Synonyms:
2-Phenyl-9-((R)-1-phenyl-ethyl)-9H-pyrimido[4,5-b]indol-4-ylamine | 2-Phenyl-9-(1-phenyl-ethyl)-9H-1,3,9-triaza-fluoren-4-ylamine | CHEMBL79415
Type:
Small organic molecule
Emp. Form.:
C24H20N4
Mol. Mass.:
364.4424
SMILES:
C[C@H](c1ccccc1)n1c2ccccc2c2c(N)nc(nc12)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: