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Target
D(1A) dopamine receptor
Ligand
BDBM50052732
Substrate
n/a
Meas. Tech.
ChEMBL_58509 (CHEMBL672004)
Ki
209±n/a nM
Citation
 Shah, JH; Kline, RH; Geter-Douglass, B; Izenwasser, S; Witkin, JM; Newman, AH (+/-)-3-[4'-(N,N-dimethylamino)cinnamyl]benzazepine analogs: novel dopamine D1 receptor antagonists. J Med Chem 39:3423-8 (1996) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50052732
Synonyms:
8-Bromo-5-phenyl-3-((E)-3-phenyl-allyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol | CHEMBL419759
Type:
Small organic molecule
Emp. Form.:
C25H24BrNO
Mol. Mass.:
434.368
SMILES:
Oc1cc2C(CN(C\C=C\c3ccccc3)CCc2cc1Br)c1ccccc1
Structure:
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