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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50053913
Substrate
n/a
Meas. Tech.
ChEMBL_157546 (CHEMBL764930)
Ki
1500±n/a nM
Citation
 Romines, KR; Morris, JK; Howe, WJ; Tomich, PK; Horng, MM; Chong, KT; Hinshaw, RR; Anderson, DJ; Strohbach, JW; Turner, SR; Mizsak, SA Cycloalkylpyranones and cycloalkyldihydropyrones as HIV protease inhibitors: exploring the impact of ring size on structure-activity relationships. J Med Chem 39:4125-30 (1996) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50053913
Synonyms:
3-(2,2-Dimethyl-1-phenyl-propyl)-4-hydroxy-4a,5,6,7,8,9,10,10a-octahydro-cycloocta[b]pyran-2-one | CHEMBL133951
Type:
Small organic molecule
Emp. Form.:
C22H30O3
Mol. Mass.:
342.4718
SMILES:
CC(C)(C)C(C1C(=O)OC2CCCCCCC2C1=O)c1ccccc1
Structure:
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